{"id":41688,"date":"2024-09-24T12:04:43","date_gmt":"2024-09-24T12:04:43","guid":{"rendered":"https:\/\/avendrapharma.com\/produkt\/fermentix-oral-solution-10-ml-x-12-vials\/"},"modified":"2024-09-24T12:04:43","modified_gmt":"2024-09-24T12:04:43","slug":"fermentix-oral-solution-10-ml-x-12-vials","status":"publish","type":"product","link":"https:\/\/avendrapharma.com\/en\/produkt\/fermentix-oral-solution-10-ml-x-12-vials\/","title":{"rendered":"Fermentix, oral solution, 10 ml x 12 vials"},"content":{"rendered":"

Indications:<\/strong>
\nMaintains the balance of normal intestinal microflora and has a beneficial effect on the natural function of the immune system;
\nHelps overcome the adverse gastrointestinal effects of antibiotic therapy;
\nHelps restore B-group vitamins after antibiotic intake;
\nSupports the restoration of the natural gastrointestinal flora. The use of broad-spectrum antibiotics leads to a reduction in normal gastrointestinal flora \u2013 dysbacteriosis (a condition caused by an imbalance of the bacteria normally found in the intestines), with possible diarrhea, constipation, and the appearance of fungal infections;
\nHelps the body recover after antibiotic therapy;
\nPromotes the normal functioning of the intestinal microbial flora;
\nHas a beneficial effect on gastrointestinal discomfort;
\nExerts a positive influence on the immune system. <\/p>\n

Mechanism of action:<\/strong>
\nFERMENTIX ORAL SOLUTION is a SYNBIOTIC (a combination of probiotics and a prebiotic) containing tyndallized bacteria. Tyndallized bacteria are heat-inactivated. There is growing interest in non-viable microorganisms for use as probiotics, primarily through the process of tyndallization. The combination of heat treatments with periods of lower temperatures (ambient, cooling, or freezing temperatures) is a process known as tyndallization, due to its similarities to the sterilization method developed by physicist Dr. John Tyndall in the 19th century. This avoids the adverse effects that live bacterial strains may have. Heat-treated probiotic cells are able to exert beneficial effects, mainly immunomodulatory, protection against enteropathogens, and maintenance of the integrity of the intestinal barrier [1].
\nVarious strains, including lactic acid bacteria and bifidobacteria, are able to induce beneficial effects in their heat-inactivated form [2].
\nHeat-killed probiotics are also able to antagonize pathogens with antimicrobial compounds and compete with pathogens for adhesion and colonization [3,4].
\nData show that heat-killed bacteria have key probiotic effects, with advantages over live probiotics (primarily their safety profile), making them preferred for managing common conditions of gastrointestinal discomfort, especially during antibiotic therapy in immunosuppressed and elderly patients [1]. After heat treatment, industrially grown probiotic bacteria, in most cases, maintain their essential probiotic properties at the intestinal level, thus allowing for the development of safer products.
\nThe main effects of probiotics are as follows:
\nBalancing and restoring the gut microbiota, protection from pathogens, immunomodulation, and maintenance of the integrity of the intestinal barrier;
\nProbiotics are able to fight pathogens by producing antimicrobial compounds;
\nThey lower pH;
\nThey inhibit the growth of pathogenic bacteria by directly binding with Gram-negative bacteria;
\nThey enhance epithelial barrier function to prevent chronic inflammation in the gut;
\nProbiotic lactobacilli and bifidobacteria regulate the production of inflammatory mediators and favorably regulate inflammation of the intestinal mucosa;
\nProbiotics can initiate the restoration of barrier function after damage induced by various pathological conditions, such as E. coli-induced mucosal disruption;
\nProbiotics, such as Lactobacillus and other lactic acid bacteria and bifidobacteria, have been shown to inhibit a wide range of enteropathogens, including E. coli, Salmonella, Helicobacter pylori, Listeria monocytogenes, and rotavirus.
\nFERMENTIX ORAL SOLUTION is useful for recovery after antibiotic treatment and infections due to its content of five B-group vitamins. Vitamins of this group are of particular importance for the body, and their levels decrease during impaired gastrointestinal function.
\nFERMENTIX ORAL SOLUTION also contains a sufficient amount of Arabinogalactan. Arabinogalactans are biologically active compounds (prebiotics). Arabinogalactan is an excellent immune system stimulator, stimulating the formation of immune cells twice as effectively as Echinacea.
\nFERMENTIX ORAL SOLUTION helps strengthen immunity weakened during illness.
\nEffects of Arabinogalactan:
\nstimulates the growth and development of beneficial intestinal microflora;
\nimproves intestinal peristalsis;
\npromotes regular cleansing of the intestinal tract;
\nadsorbs and removes toxic substances, radionuclides, and heavy metals;
\nstrengthens the immune system;
\nprotects against the negative consequences of antibiotic therapies, protecting the beneficial intestinal microflora from the damaging action of the antibiotic. Microbial Arabinogalactan is a major structural component of the mycobacterial cell wall [5] [6];
\ncontributes to increasing the therapeutic effect when used simultaneously with probiotic preparations containing live lacto- and bifidobacteria;
\nArabinogalactan is effective for modulating the immune response against the invasion of pathogenic microorganisms [7]. <\/p>\n

REFERENCES:<\/strong>
\n1. Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview, Published: 23 May 2019
\n2. N\u00faria Piqu\u00e9, Mercedes Berlanga, David Mi\u00f1ana-Galbis. Microbiology Section, Department of Biology, Healthcare and Environment,
\n3. Faculty of Pharmacy and Food Sciences, Universitat de Barcelona (UB), Av Joan XXIII, 27-31, 08028 Barcelona, Catalonia, Spain; mberlanga@ub.edu (M.B.); davidminyana@ub.edu (D.M.-G.)
\n4. Institut de Recerca en Nutrici\u00f3 i Seguretat Aliment\u00e0ria de la UB (INSA-UB), Universitat de Barcelona
\n5. Deshpande, G.; Athalye-Jape, G.; Patole, S. Para-probiotics for Preterm Neonates. Next. Front. Nutr. 2018
\n6. Kim, K.W.; Kang, S.S.; Woo, S.J.; Park, O.J.; Ahn, K.B.; Song, K.D.; Lee, H.K.; Yun, C.H.; Han, S.H. Lipoteichoic Acid of Probiotic Lactobacillus plantarum Attenuates Poly I:C-Induced IL-8 Production in Porcine Intestinal Epithelial Cells. Front. Microbiol. 2017
\n7. Liu, Z.; Zhang, Z.; Qiu, L.; Zhang, F.; Xu, X.; Wei, H.; Tao, X. Characterization and bioactivities of the exopolysaccharide from a probiotic strain of Lactobacillus plantarum WLPL04. J. Dairy Sci. 2017
\n8. Esko, Jeffrey D.; Tamara L. Doering; Christian R.H. Raetz (2008). in Essentials of Glycobiology. Cold Spring Harbor Press. pp. Ch.
\n9. Jump up to: a b c d e Bhamidi S (2009). \u201eMycobacterial Cell Wall Arabinogalactan\u201c. Bacterial Polysaccharides: Current Innovations and Future Trends. Caister Academic Press
\n7. Udani et al., 2010, Germany <\/p>\n

Packaging:<\/strong>
\nCardboard box with 12 oral vials of 10 ml each.
\nBatch number: see packaging.
\nNet quantity: 120 ml E<\/p>\n

Manufacturer:<\/strong>
\nPHYTO GARDA, Italy.
\nPHYTO GARDA SRL
\nVIA S.ISIDORO, 4 \u2013 LOC. VANZELLE
\n37010 RIVOLI VERONESE (VR) \u2013 ITALY <\/p>\n

Official Representative for Bulgaria:<\/strong>
\nAVENDRA PHARMA EOOD
\nwebsite: www.avendrapharma.com
\ne-mail: info@avendrapharma.com
\nhead office: 3 Pleven St., Ruse
\ntel.: +359 888 575 008.
\ncentral warehouse: 101 Nikolaevska St., Ruse<\/p>\n

 <\/p>\n

QUANTITATIVE COMPOSITION:<\/strong>
\nContent in the recommended daily dose (2 vials):
\nIngredients: 1 vial (10 ml) 2 vials (20 ml)
\n– Arabinogalactan 250 mg 500 mg
\n– Tyndallized lactic acid bacteria
\n– Lactobacillus acidophilus 8 x 10\u2079 cfu\/g 16 x 10\u2079 cfu\/g
\n– Lactobacillus casei 2 x 10\u2079 cfu\/g 4 x 10\u2079 cfu\/g
\n– B-group vitamins
\n– Vitamin B3 4.8 mg 9.6 mg
\n– Vitamin B2 0.42 mg 0.84 mg
\n– Vitamin B6 0.42 mg 0.84 mg
\n– Vitamin B1 0.33 mg 0.66 mg
\n– Vitamin B12 0.75 \u00b5g 1.5 \u00b5g
\n– May contain traces of soy and lactose.
\n– Gluten-free.<\/p>\n

EXCIPIENTS:<\/strong>
\n– water
\n– sweetener: fructose
\n– preservatives: citric acid \/E330\/, potassium sorbate \/E202\/, sodium benzoate \/E211\/
\n– flavor<\/p>\n

 <\/p>\n

Dosage and administration:<\/strong>
\nTake 1 \u2013 2 vials daily, with or without further dilution of the contents in liquid.
\nTake between meals or after a meal.
\nShake the vial well before use.<\/p>\n

Contraindications:<\/strong>
\nDo not take if you have a known allergy to any of the ingredients.<\/p>\n

Special warnings:<\/strong>
\nDo not exceed the recommended daily dose.
\nDo not administer to children under 3 years of age.
\nDo not use as a substitute for a varied and balanced diet.
\nKeep out of reach of young children.
\nYou may notice a change in color, smell, or observe a sediment at the bottom of the vial, which disappears upon shaking. This is a natural result of the nature of the ingredients used and does not mean the product is unfit for use.
\nIn case of pregnancy and breastfeeding, consult a doctor before taking this product.<\/p>\n

Instructions for use:<\/strong>
\nSee dosage and administration.<\/p>\n

Side effects:<\/strong>
\nNone known.<\/p>\n

Shelf life and storage:<\/strong>
\nStore in a cool, dry place at temperatures up to 25\u00b0C, away from sunlight.
\nDo not use if the packaging is damaged or missing.
\nUse by: see the date marked on the packaging.<\/p>\n","protected":false},"excerpt":{"rendered":"

FERMENTIX ORAL SOLUTION is a SYNBIOTIC (a combination of probiotics and a prebiotic) containing tyndallized (heat-treated) bacteria with added B-group vitamins and arabinogalactan. It is the product of choice for body recovery after antibiotic therapy, as well as during and after gastrointestinal discomfort, with an excellent safety and tolerance profile. Available in convenient oral vials with a pleasant cherry aroma. <\/p>\n","protected":false},"featured_media":41691,"template":"","meta":[],"product_brand":[],"product_cat":[194,183],"product_tag":[],"class_list":["post-41688","product","type-product","status-publish","has-post-thumbnail","product_cat-all-products","product_cat-uncategorized","description-off","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/product\/41688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/media\/41691"}],"wp:attachment":[{"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/media?parent=41688"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/product_brand?post=41688"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/product_cat?post=41688"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/avendrapharma.com\/en\/wp-json\/wp\/v2\/product_tag?post=41688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}